Processing steps , such as decellularization , lyophilization , disinfection , and terminal sterilization , may affect the morphology and composition of an ecm scaffold , including , but not limited to , the integrity of a basement membrane complex 處理時的每一步,比如去細胞、低壓凍干、消毒以及最終的滅菌都會影響ecm支架的形態(tài)和組分,也會破壞基底膜復(fù)合物的結(jié)構(gòu)完整性。